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Thomas Pelham-Holles, Duke of Newcastle – Returning to office with Pitt the Elder as Southern Secretary, this government helped steer Britain to ultimate victory over France and Spain during the Seven Years’ War.
John Stuart, 3rd Earl of Bute – A favourite of George III, he was the first Scot to hold the top office.
Unable to control the coalition, he resigned the office.
William Cavendish-Bentinck, 3rd Duke of Portland – Although aged and in poor health, Portland assumed the top job for the second time.
William Petty, 2nd Earl of Shelburne – Britain’s first Irish-born Prime Minister, a former general he was in office at the time of the Treaty of Paris which officially ended the American War of Independence.