dating a czech man - Least sedating second generation antihistamine

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least sedating second generation antihistamine-58

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They act on histamine-1 receptors in the periphery and are unlikely to penetrate the brain, so are less likely to cause side effects or interact with drugs.

Most second-generation antihistamines do not cause drowsiness, although some (such as cetirizine and fexofenadine), may be more likely to do so at higher dosages.

In the case of an allergy, however, the release of histamine is actually unnecessary because the allergen is not the threat that the immune system mistakes it for.

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